Nicola De Stefano

This paper improves the BIANCA tool for WMH segmentation by introducing a locally adaptive thresholding method, LOCATE, which significantly enhances segmentation performance compared to global thresholding.

This study finds that multiple sclerosis accelerates brain ageing, with older-appearing brains linked to faster disability progression.

This study identifies the sequence of grey matter atrophy progression in multiple sclerosis using longitudinal MRI data and shows its association with disability accumulation in relapsing-remitting MS.

This study shows that deep grey matter volume loss predicts faster disability progression in multiple sclerosis, with specific patterns in different disease subtypes.