Author

David E. Hoke

Monash UniversityORCID 0000-0003-4975-4391Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Ashley M. BuckleiD· 1 shared Benjamin T. PorebskiiD· 1 shared Cyril F. RebouliD· 1 shared Daniel ChristiD· 1 shared Daniel E. WilliamsiD· 1 shared Dominika ElmlundiD· 1 shared Gustavo FenaltiiD· 1 shared James FodoriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Ashley M. BuckleORCID

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedMar 7, 2025

Structure and dynamics of the autoantigen GAD65 in complex with the human autoimmune polyendocrine syndrome type 2-associated autoantibody b96.11

Susanne H. D. Ständer, Cyril F. Reboul, Sarah N. Le…·Ashley M. Buckle

This study characterizes the structure and dynamics of GAD65 and its interaction with autoantibody b96.11, revealing how intrinsic conformational flexibility drives autoantigenicity.

10 citations

humanstructural biology

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