Genetic & Genomic MedicineNature GeneticsPeer-reviewed
Genome-wide analysis in 756,646 individuals provides first genetic evidence that ACE2 expression influences COVID-19 risk and yields genetic risk scores predictive of severe disease
Julie E. Horowitz, Jack A. Kosmicki, Amy Damask…·Arden Moscati
The paper identifies a rare variant that lowers ACE2 expression and reduces COVID-19 risk, and develops a genetic risk score predicting severe disease.
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