Author

Sarah X. Morillo Leonardo

ETH ZurichORCID 0009-0000-0503-5606Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:scRNA-seq· 2 Approach:benchmark study· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Charlotte SonesoniD· 1 shared Daan H. de GrootiD· 1 shared Erik van NimwegeniD· 1 shared Helena Lucia CrowelliD· 1 shared Mark D. RobinsoniD· 1 shared Mikhail V. PachkoviD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 6 mutual co-author links

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1 shared paperBioinformatics

Charlotte SonesonORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMay 8, 2025

Bonsai: Tree representations for distortion-free visualization and exploratory analysis of single-cell omics data

Daan H. de Groot, Sarah X. Morillo Leonardo, Mikhail V. Pachkov, Erik van Nimwegen

Bonsai provides a tree-based visualization method for single-cell omics data that accurately represents distances and structures without distortion, offering novel biological insights.

3 citations

humanscRNA-seq

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BioinformaticsbioRxivPreprintNov 15, 2021

Built on sand: the shaky foundations of simulating single-cell RNA sequencing data

Helena Lucia Crowell, Sarah X. Morillo Leonardo, Charlotte Soneson, Mark D. Robinson

This paper evaluates synthetic scRNA-seq data generators, finding they often introduce artificial effects and fail to accurately mimic real data for method comparisons.

16 citations

scRNA-seqbenchmark study

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