NeuroscienceCommunications BiologyPeer-reviewed
Sex-focused analyses of M83 A53T hemizygous mouse model with recombinant human alpha-synuclein preformed fibril injection identifies female resilience to disease progression: A combined magnetic resonance imaging and behavioural study.
Stéphanie Tullo, Janice Park, Daniel Gallino…·M. Mallar Chakravarty
The paper investigates sex differences in aSyn pathology progression in M83 mice using MRI and behavioral analysis, finding female resilience to neurodegeneration despite earlier motor symptom onset in males.