In vivo and in silico alpha-synuclein propagation dynamics: The role of genotype, epicentre, and connectivity
Stéphanie Tullo, Janice Park, Shady Rahayel, Daniel Gallino, Megan Park, Kristie Mar, Ying‐Qiu Zheng, Esther del Cid‐Pellitero, Edward A. Fon, Wen Luo, Irina Shlaifer, Thomas M. Durcan, Bratislav Mišić, Alain Dagher, Gabriel A. Devenyi, M. Mallar Chakravarty
This study investigates how alpha-synuclein propagation affects brain atrophy and motor deficits across different genotypes and inoculation sites in mice.
bioRxiv · Jul 18, 2025 · PreprintNeuroscience