Author

Thussenthan Walter Angelo

Pennsylvania State UniversityORCID 0009-0000-2861-8425Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:scATAC-seq· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Yasin UzuniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintApr 14, 2026

SPEAR: Predicting Gene Expression from Single-Cell Chromatin Accessibility

Thussenthan Walter Angelo, Yasin Uzun

SPEAR predicts gene expression from chromatin accessibility in single-cell multiome data, showing that transformer models achieve the highest correlation across two biological systems.

DOI 10.64898/2026.04.13.717809

mousehuman

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