BiophysicsbioRxivPreprint
Cleaved vs. Uncleaved: How Furin Cleavage Reshapes the Conformational Landscape of SARS-CoV-2 Spike
Natesan Mani, Raghavendran Suresh, Srirupa Chakraborty
This study compares cleaved and uncleaved SARS-CoV-2 Spike proteins using MD simulations, showing cleavage alters conformational dynamics and allosteric communication, potentially affecting receptor binding.
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