Author

Margarita Pertseva

ETH ZurichORCID 0009-0000-5561-784XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:clustering· 1 Approach:contrastive learning· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1

Frequent Co-Authors

Sai T. ReddyiD· 2 shared Beichen GaoiD· 1 shared Ben MurrelliD· 1 shared Cédric R. WeberiD· 1 shared Daniel J. ShewardiD· 1 shared Daniele ScarcellaiD· 1 shared Jiami HaniD· 1 shared Joseph M. TaftiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersSynthetic Biology

Sai T. ReddyORCID

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2 papers

Recent·Most cited

Synthetic coevolution reveals adaptive mutational trajectories of neutralizing antibodies and SARS-CoV-2

Roy A. Ehling, Mason Minot, Max D. Overath, Daniel J. Sheward, Jiami Han, Beichen Gao, Joseph M. Taft, Margarita Pertseva, Cédric R. Weber, Lester Frei, Thomas Bikias, Ben Murrell, Sai T. Reddy

This study uses synthetic coevolution to explore mutational trajectories between neutralizing antibodies and SARS-CoV-2 variants, revealing antagonistic and compensatory mutations.

Cell Systems · Sep 1, 2025Peer-reviewedSynthetic Biology

TCR clustering by contrastive learning on antigen specificity.

Margarita Pertseva, Océane M. Follonier, Daniele Scarcella, Sai T. Reddy

This paper introduces TouCAN, a contrastive learning method for clustering TCR sequences and predicting antigen specificity, showing comparable performance to existing methods.

bioRxiv · Apr 4, 2024 · PreprintBioinformatics