Author

Brian S. Plosky

Arc Research InstituteORCID 0009-0000-5892-3017Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:deep learning· 2 Organism:human· 2 Approach:transformer / foundation model· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Abhinav AdduriiD· 2 shared Chiara Ricci-TamiD· 2 shared Dave P. Burke· 2 shared Hani GoodarziiD· 2 shared Patrick D. HsuiD· 2 shared Adam Krejčí· 1 shared Adibvafa FallahpouriD· 1 shared Aidan F. WintersiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersSystems Biology

Abhinav AdduriORCID

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2 papers

Recent·Most cited

Systems BiologyCellPeer-reviewedAug 31, 2026

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Predicting cellular responses to perturbation across diverse contexts with STATE

Abhinav Adduri, Dhruv Gautam, Beatrice Bevilacqua…·Yusuf Roohani

State, a set-based transformer trained on over 100 million perturbed cells, predicts perturbation responses in new cellular contexts better than mean, linear and deep learning baselines.

100 citationstop 1%

humanscRNA-seq

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Molecular BiologybioRxivPreprintJul 19, 2026

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BioReason-Pro: Advancing Protein Function Prediction with Multimodal Biological Reasoning

Adibvafa Fallahpour, Arman Seyed-Ahmadi, Parsa Idehpour…·Bo Wang

A reasoning LLM combining ESM3 embeddings with GO-GPT term predictions produces protein function annotations that experts rated tie-or-better than UniProt in 79% of cases (SFT model).

4 citations

humanmultiple species

𝕏 PostBluesky