Philipp T. Kaulich

This paper introduces a workflow that decouples quantification and identification in label-free top-down proteomics, improving proteome coverage and quantification precision.

This paper introduces a 2D nanoLCxCZE-MS platform for deep top-down proteomics, significantly increasing proteoform identification in human colon cancer samples.

The paper introduces TopRepo, a comprehensive TD-MS spectral repository, and shows it improves proteoform identification and supports DL model training for spectral prediction.

FLASHQuant is a fast, accurate, and open-source algorithm for label-free quantification of proteoforms in top-down proteomics, resolving co-eluting signals efficiently.