Uncovering the Genomic Manifold via Scalable Learning from the Global Microbiome
Weimin Wu, Zhihan Zhou, Robert W. Riley, Mohammad Abdulqader, Xuefeng Song, Satria Ardhe Kautsar, Rob S Egan, Steven A. Hofmeyr, Gefei Liu, Shira Goldhaber-Gordon, Mutian Yu, Harrison Ho, Yaping Liu, Andrei Stecca Steindorff, Fengchen Liu, , Zhong Wang
The paper introduces GenomeOcean, a large-scale generative model trained on metagenomic data, to explore the genomic manifold hypothesis and demonstrates its alignment with another model.
bioRxiv · Jan 30, 2025 · PreprintBioinformatics