Andrei Stecca Steindorff

MAESTRO uncovers tandem paralog dynamics as a core driver of fungal stress adaptation

MAESTRO identifies tandem paralog copy number variation as a key mechanism for stress adaptation in Pichia kudriavzevii, linking it to drug resistance and environmental tolerance.

Uncovering the Genomic Manifold via Scalable Learning from the Global Microbiome

The paper introduces GenomeOcean, a large-scale generative model trained on metagenomic data, to explore the genomic manifold hypothesis and demonstrates its alignment with another model.

Improved gene annotation of the fungal wheat pathogen Zymoseptoria tritici based on combined Iso-Seq and RNA-Seq evidence

The paper improves gene annotation of Zymoseptoria tritici by combining Iso-Seq and RNA-Seq data, resulting in more accurate gene models and new insights into its transcriptional landscape.