Lucy Dillon

The paper identifies gene co-occurrence patterns in bacterial genomes that reveal fitness trade-offs constraining resistance mechanisms, showing species-specific gene combination rules.

This study characterizes a multidrug-resistant E. coli strain from a sepsis patient using whole-genome sequencing and phenotypic testing, revealing extensive AMR genes and taxonomic ambiguity with related species.

The paper uses machine learning to predict antimicrobial resistance phenotypes from genomic data across 28 bacterial genera, identifying 528 species-specific genomic pathways to resistance.