GenomicsbioRxivPreprint
Time-resolved single-cell screening reveals the dynamic regulatory architecture of human cardiogenesis
Dominik Lindenhofer, Katharina Mikulik, Stefanie Mantz…·Lars Michael Steinmetz
This study uses time-resolved single-cell CRISPR screening and a multiome atlas to uncover dynamic gene regulatory networks in human cardiogenesis, identifying stage-specific regulators and CHD-linked gene functions.