GeneticsPLoS GeneticsPeer-reviewed
MR-SPLIT: a novel method to address selection and weak instrument bias in one-sample Mendelian randomization studies
Ruxin Shi, Ling Wang, Stephen Burgess, Yuehua Cui
MR-SPLIT reduces bias in one-sample Mendelian randomization by addressing weak instruments and selection bias through sample-splitting and cross-fitting.