NeuroscienceEMBO Molecular MedicinePeer-reviewed
Enhanced Notch dependent gliogenesis and delayed physiological maturation underlie neurodevelopmental defects in Lowe syndrome
Yojet Sharma, Priyanka Bhatia, Gagana Rangappa…·Padinjat Raghu
This study identifies enhanced Notch signaling and gliogenesis in Lowe syndrome patient-derived neural cultures, linked to OCRL dysfunction and neurodevelopmental defects.