Author

Elisa Scanu

Queen Mary University of LondonORCID 0009-0001-9989-5822Unclaimed ORCID profile · follow to get notified of new preprints

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Cancer Biology· 1

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Approach:statistical model· 1

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Benjamin WerneriD· 1 shared Weini HuangiD· 1 shared

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1 shared paperCancer Biology

Benjamin WernerORCID

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Cancer BiologybioRxivPreprintOct 22, 2024

The maintenance and de-mixing of extrachromosomal DNA variants in single cells

Elisa Scanu, Benjamin Werner, Weini Huang

This study develops computational models to show that mixed ecDNA subpopulations in tumour cells require variant switching and a positive fitness of ecDNA+ cells, not direct co-selection.

DOI 10.1101/2024.10.22.619675

statistical model

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