Depression in Parkinson's disease is associated with dopamine unresponsive reduced reward sensitivity during effort-based decision making
Harry Costello, Yumeya Yamamori, Karel Kieslich, Mackenzie Murphy, Kamilla Bobyreva, Anette E. Schrag, Robert J. Howard, Jonathan Paul Roiser
This study shows that depression in Parkinson's disease is linked to reduced reward sensitivity in effort-based decision making, which is not improved by dopamine medication.
bioRxiv · May 9, 2024 · PreprintNeuroscience