Anette E. Schrag

Comparison of Automated White Matter Lesion Segmentation Approaches for Use in Large, Multi-Site Data Analyses in Parkinson's Disease

This paper evaluates automated white matter lesion segmentation methods in Parkinson's disease and healthy controls, finding U-Net-pgs to be the most accurate and reliable approach across multiple metrics and datasets.

The ENIGMA-PD-WML Pipeline: A Containerized, User-Friendly Approach for Accurate, Standardized Segmentation of White Matter Lesions in Multi-Site MRI Data

Parkinson's Families Project: a UK-wide study of early onset and familial Parkinson's disease

The paper reports genetic findings from a UK-wide study of early-onset and familial Parkinson's disease, identifying pathogenic variants in known PD genes and highlighting the need for further monogenic causes.

Depression in Parkinson's disease is associated with dopamine unresponsive reduced reward sensitivity during effort-based decision making

This study shows that depression in Parkinson's disease is linked to reduced reward sensitivity in effort-based decision making, which is not improved by dopamine medication.

Genome-wide Association Study identifies two novel loci for Gilles de la Tourette Syndrome

This study identifies two novel genetic loci associated with Tourette Syndrome through a genome-wide meta-analysis and integrates functional data to implicate specific genes.

Whole genome sequencing for diagnosis of neurological repeat expansion disorders

This study demonstrates that whole genome sequencing can effectively detect repeat expansions in neurological disorders with high sensitivity and specificity, enabling diagnosis in previously undiagnosed patients.

Parkinsons disease determinants, prediction and gene-environment interactions in the UK Biobank

The paper investigates environmental and genetic risk factors for Parkinson's disease using UK Biobank data, showing gene-environment interactions and improved prediction with polygenic risk scores.

Screening performance of abbreviated versions of the UPSIT smell test

The paper evaluates abbreviated versions of the UPSIT smell test to detect hyposmia, finding that a 4-item test outperforms existing shorter versions in sensitivity and specificity.