TaHL-PTM: Post-Translational Modification Prediction in Proteins via Target-Hooked Discriminative Fine-Tuning of Decoder-only Protein Language Models
Bhawana Prasain, Pawel Pratyush, Stefan Schulze, Dukka B. KC
TaHL-PTM improves PTM prediction by addressing tokenization issues in decoder-only PLMs, achieving better performance on residue-level tasks.
bioRxiv · Aug 27, 2026 · PreprintBioinformatics