Author

Yogesh Purushotham

Beth Israel Deaconess Medical CenterORCID 0009-0002-2010-3878Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:GWAS summary statistics· 1 Approach:statistical model· 1

Frequent Co-Authors

Tamar SoferiD· 1 shared Xiaonan LiuiD· 1 shared Yu‐Jyun HuangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Tamar SoferORCID

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1 paper

Recent·Most cited

Reassessing Instrument Strength in Two-Sample Mendelian Randomization Analysis

Xiaonan Liu, Yu‐Jyun Huang, Yogesh Purushotham, Tamar Sofer

This study evaluates the impact of weak instrumental variables in two-sample Mendelian randomization, showing they can weaken effect estimates in small samples but are less harmful in large ones.

medRxiv · Jun 19, 2026 · PreprintGenetic & Genomic Medicine