Author

Rui Niu

Northwestern Polytechnical UniversityORCID 0009-0002-2781-6176Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Organism:human· 1 Approach:large language model· 1 Assay:proteomics· 1

Frequent Co-Authors

Ji-Ren Zhou· 1 shared Xiaoying KongiD· 1 shared Xuequn ShangiD· 1 shared Yanli LiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperImmunology

Ji-Ren Zhou

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintJun 27, 2025

TridentTCR: Predicting T Cell Receptor Specificity for Antigens and Autoimmune-Related Targets via a Topology-Aware Graph and Large Language Model

Rui Niu, Xiaoying Kong, Ji-Ren Zhou…·Xuequn Shang

TridentTCR predicts TCR specificity for antigens and autoimmune targets using a graph neural network and large language model, achieving better classification and identifying cross-reactivity in type 1 diabetes.

DOI 10.1101/2025.06.27.661632

humanproteomics

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