Author

Alla Polozova

Amgen (United States)ORCID 0009-0002-3029-791XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Approach:deep learning· 1

Frequent Co-Authors

Natesan ManiiD· 2 shared Srirupa ChakrabortyiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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2 shared papersImmunology

Natesan ManiORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 17, 2026

Oligomannose Fc Glycans Reprogram the Energetic and Conformational Basis of CD16a Recognition

Natesan Mani, Alla Polozova, Srirupa Chakraborty

This study uses molecular dynamics simulations to show how oligomannose Fc glycans alter CD16a binding by changing energetic interactions and conformational dynamics.

DOI 10.64898/2026.08.07.738819

protein structuremechanistic / dynamical model

𝕏 PostBluesky

BiophysicsbioRxivPreprintJul 1, 2026

Molecular Basis of Core Fucosylation-Dependent Modulation of IgG1-FcCD16a Binding

Natesan Mani, Alla Polozova, Srirupa Chakraborty

This study investigates how core fucosylation affects IgG1-FcCD16a binding through molecular dynamics simulations, revealing structural and dynamic changes that reduce ADCC.

DOI 10.64898/2026.06.26.732000

protein structuredeep learning

𝕏 PostBluesky