Author

Harley I. Richker

Arizona State UniversityORCID 0009-0002-6064-4126Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Approach:comparative / phylogenetic analysis· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Carlo C. MaleyiD· 2 shared Bailey S. KaneiD· 1 shared Barbara Natterson-HorowitziD· 1 shared Beckett SterneriD· 1 shared Bryan Yavari· 1 shared Cristina BaciuiD· 1 shared Diego MalloiD· 1 shared Hannah Human· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Carlo C. MaleyORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 4, 2026

The Fitness Cost of Therapeutic Resistance in Cancer: A Systematic Review

Bailey S. Kane, Lauren Mestas, Madds Garza…·Carlo C. Maley

This paper reviews 49 experiments showing that therapy-resistant cancer clones often have a fitness cost, with two-thirds demonstrating competitive disadvantage in untreated environments.

DOI 10.64898/2025.12.29.696883

humanbenchmark study

𝕏 PostBluesky

Evolutionary BiologyEvolution Medicine and Public HealthPeer-reviewedDec 23, 2025

Leveraging Comparative Phylogenetics for Evolutionary Medicine: Applications to Comparative Oncology

Walker J Compton Mellon, Beckett Sterner, J. Arvid Ågren…·Zachary Taylor Compton

This paper argues for integrating phylogenetic comparative methods into evolutionary medicine, using comparative oncology to show how these methods can reveal evolutionary patterns in disease traits.

2 citations

comparative / phylogenetic analysisphylogenetics / evolution

𝕏 PostBluesky