Author

Longyu Li

Jilin UniversityORCID 0009-0002-6572-3544Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

Hao ZhangiD· 1 shared Junqi WuiD· 1 shared Liyan DongiD· 1 shared Nuo JiaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBioinformatics

Hao ZhangORCID

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1 paper

Recent·Most cited

Decoupling Structure and Property in Discrete Protein Diffusion: Alignment Dynamics and Collapse Mechanisms

Junqi Wu, Liyan Dong, Nuo Jia, Longyu Li, Hao Zhang

This paper investigates the temporal dynamics of discrete protein diffusion models, revealing a decoupling between structural alignment and property optimization, and identifies a structural collapse regime due to Coulombic repulsion.

bioRxiv · Feb 8, 2026 · PreprintBioinformatics