BioinformaticsInternational Journal of Molecular SciencesPeer-reviewed
In silico investigation of the new UK (B.1.1.7) and South African (501Y.V2) SARS-CoV-2 variants with a focus at the ACE2-Spike RBD interface
Bruno O. Villoutreix, Vincent Cálvez, Anne‐Geneviève Marcelin, Abdel‐Majid Khatib
The paper investigates the impact of amino acid substitutions in SARS-CoV-2 Spike protein on ACE2 binding using in silico methods, finding that N501Y increases affinity while K417N and E484K may reduce it.
89 citationstop 3%