Age at Onset and Liability to Disorder: Estimating Covariances in Censored Populations
Michael Churton Neale, HERMINE H. M. MAES, Lanie K. Mullins, Madhurbain Singh, Jared V. Balbona, Robert M. Kirkpatrick, Timothy R. Brick, Michael D. Hunter, Steven M. Boker, Luís Fernando Silva Castro-de-Araujo, Andrew Joseph Schork, Morten Dybdahl Krebs, Joel Mefford
The paper estimates the covariance between liability to a disorder and age at onset in censored populations using a mixture distribution model applied to twin data.
medRxiv · Sep 3, 2026 · PreprintGenetic & Genomic Medicine