Author

Sander Goossens

Delft University of TechnologyORCID 0009-0002-7161-0132Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Colm SealeiD· 1 shared Joana P. GonçalvesiD· 1 shared Yasin I. TepeliiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperBioinformatics

Colm SealeORCID

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1 paper

Recent·Most cited

SNMF: Integrated Learning of Mutational Signatures and Prediction of DNA Repair Deficiencies

Sander Goossens, Yasin I. Tepeli, Colm Seale, Joana P. Gonçalves

The paper introduces SNMF, a supervised method to learn mutational signatures and predict DNA repair deficiencies, achieving high accuracy in cell lines and predicting DDR status in tumors.

bioRxiv · Nov 27, 2024 · PreprintBioinformatics