Yasin I. Tepeli

SNMF: Integrated Learning of Mutational Signatures and Prediction of DNA Repair Deficiencies

The paper introduces SNMF, a supervised method to learn mutational signatures and predict DNA repair deficiencies, achieving high accuracy in cell lines and predicting DDR status in tumors.

A Metagenomic Study of Antibiotic Resistance Across Diverse Soil Types and Geographical Locations

This study analyzes antibiotic resistance patterns in soil metagenomes across different types and locations, identifying key resistance genes and their environmental influences.

ELISL: Early-Late Integrated Synthetic Lethality Prediction in Cancer

ELISL improves synthetic lethality prediction in cancer by integrating context-specific and context-free data, showing better performance and robustness across 8 cancer types.

PAMOGK: A Pathway Graph Kernel based Multi-Omics Clustering Approach for Discovering Cancer Patient Subgroups

PAMOGK integrates multi-omics data with pathway knowledge to cluster cancer patients, identifying subgroups with distinct survival and clinical features in kidney renal clear cell carcinoma.