ImmunologyCell ReportsPeer-reviewed
Jagged-1+ Tregs Mediate Lymphatic Remodeling in Tumour-Draining Lymph Nodes
Jessie Z. Xu, Pei-Hsun Tsai, Prudence PokWai Lui…·Niwa Ali
This study shows that Jag1-expressing regulatory T cells (Tregs) in tumor-draining lymph nodes (tdLNs) are essential for lymphatic remodeling and niche formation during melanoma progression.