Optimization of High Molecular Weight DNA Extractions from Dried, Museum-Grade Insects Enables Long-Read Sequencing, Phylogenetics, and Methylation Profiling
Gabrielle A. Hartley, Richard J Green, Nicole Pauloski, Nicole M Tillquist, Phoebe Johnston, Sara Ord, Rachel J. Waugh O'Neill
This paper develops a DNA extraction protocol for museum-grade insects, enabling long-read sequencing, phylogenetics, and methylation profiling from degraded samples.
bioRxiv · Jul 21, 2026 · PreprintGenomics