Brain microvascular endothelial cell dysfunction during Plasmodium infection does not result from astrocyte-derived wingless-related integration site (Wnt)7a deficiency
Marshall Roedel, Nia Brooks, Jared N. Andersen, Douglas H. Cornwall, Rohan Doddavaram, Kennedy Chastang, Leah Rubner, Tao Liu, Tracey J. Lamb
This study investigates whether astrocyte-derived Wnt7a deficiency contributes to BMEC dysfunction during Plasmodium infection, finding no protective effect of Wnt7a overexpression on cerebral malaria outcomes.
bioRxiv · Oct 23, 2026 · PreprintImmunology