Integrating theory and machine learning to reveal determinants of plasmid copy number
Iqra Shahzadi, Wenzhi Xue, Hasan Ubaid Ullah, Rohan Maddamsetti, Lingchong You, Teng Wang
The paper develops a machine learning model to predict plasmid copy numbers using protein domains and applies it to metagenomic and clinical plasmid data to identify ecological patterns.
Nature Communications · Apr 22, 2026Peer-reviewedMicrobiology