Author

Wenzhi Xue

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:gene regulatory network inference· 2 Approach:machine learning (classical)· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Approach:large language model· 1 Assay:metagenomics· 1 Research Focus:protein design· 1

Frequent Co-Authors

Teng WangiD· 3 shared Ahmadreza ArghaiD· 1 shared Chengguang GaniD· 1 shared Hamid Alinejad-RoknyiD· 1 shared Hasan Ubaid Ullah· 1 shared iarui Jin· 1 shared Iqra ShahzadiiD· 1 shared Juken HongiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersMicrobiology

Teng WangORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Plasmid biology is compressed in host chromosomal architecture

yahui hou, Wenzhi Xue, Teng Wang

The paper uses machine learning to show that host chromosomal gene content predicts plasmid biology traits like carriage status and mobility potential across prokaryotic genomes.

bioRxiv · Aug 12, 2026 · PreprintMicrobiology

Decoding Prokaryotic Whole Genomes with a Product-Contextualized Large Language Model

Shiwen Ni, Shuaimin Li, Shijian Wang, Wenzhi Xue, Luoxi Zhang, Liyang Fan, Xinping Bi, Yitai Li, Chengguang Gan, iarui Jin, Yuan Lu, Ahmadreza Argha, Hamid Alinejad-Rokny, Tong Si, Min Yang, Teng Wang

The paper introduces GenSyntax, a large language model for prokaryotic genomes that captures functional context, achieving competitive performance in genome-scale tasks.

bioRxiv · Aug 9, 2026 · PreprintGenomics

Integrating theory and machine learning to reveal determinants of plasmid copy number

Iqra Shahzadi, Wenzhi Xue, Hasan Ubaid Ullah, Rohan Maddamsetti, Lingchong You, Teng Wang

The paper develops a machine learning model to predict plasmid copy numbers using protein domains and applies it to metagenomic and clinical plasmid data to identify ecological patterns.

Nature Communications · Apr 22, 2026Peer-reviewedMicrobiology

Emergence of alternative stable states in microbial communities undergoing horizontal gene transfer

Juken Hong, Wenzhi Xue, Teng Wang

This study shows that horizontal gene transfer promotes alternative stable states in microbial communities through various mechanisms.

eLife · Mar 3, 2025Peer-reviewedSystems Biology