BioinformaticsbioRxivPreprint
HEDeST: An Integrative Approach to Enhance Spatial Transcriptomic Deconvolution with Histology
Luca Gortana, Loïc Chadoutaud, Raphaël Bourgade…·Thomas Walter
HEDeST improves spatial transcriptomic deconvolution by integrating histology features, achieving single-cell resolution and outperforming existing methods in simulated and real cancer datasets.
DOI 10.64898/2026.01.06.697922