BioinformaticsbioRxivPreprint
Uncertainty-aware synthetic lethality prediction with pretrained foundation models
Kailey Hua, Ellie Haber, Jian Ma
This paper predicts synthetic lethal gene pairs using a foundation model-based framework with uncertainty calibration, improving performance without relying on PPI or GO data.
DOI 10.64898/2026.02.25.708096