NeurosciencebioRxivPreprint
Small fibre neuropathy in Fabry disease: a human-derived neuronal in vitro disease model
Thomas C. Klein, Julia Grüner, Maximilian Breyer…·Nurcan Üçeyler
This study creates a neuronal in vitro model of Fabry disease to investigate small fibre neuropathy mechanisms, finding Gb3 accumulation, altered ion channel function, and mitochondrial trafficking issues.
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