Author

Kwame Okrah

GenentechORCID 0009-0003-7210-5741Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:dimensionality reduction· 1 Assay:metagenomics· 1

Frequent Co-Authors

Héctor Corrada BravoiD· 2 shared Stephanie C. HicksiD· 2 shared ERIC V. SLUDiD· 1 shared John F QuackenbushiD· 1 shared Joseph Nathaniel PaulsoniD· 1 shared M. S. Binoj KumariD· 1 shared Rafael A. IrizarryiD· 1 shared Sridhar S. HannenhalliiD· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 19 mutual co-author links

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2 shared papersGenomics

Héctor Corrada BravoORCID

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2 papers

Recent·Most cited

GenomicsBMC GenomicsPeer-reviewedNov 6, 2018

Analysis And Correction Of Compositional Bias In Sparse Sequencing Count Data

M. S. Binoj Kumar, ERIC V. SLUD, Kwame Okrah…·Héctor Corrada Bravo

The paper addresses compositional bias in sparse sequencing count data by proposing an empirical Bayes normalization approach and clarifying assumptions of existing scaling methods.

121 citations

metagenomicsstatistical model

𝕏 PostBluesky

GenomicsBiostatisticsPeer-reviewedMay 15, 2017

Smooth Quantile Normalization

Stephanie C. Hicks, Kwame Okrah, Joseph Nathaniel Paulson…·Héctor Corrada Bravo

This paper introduces a normalization method for genomic data that accounts for biological differences in distributions while reducing technical variation.

142 citationstop 3%

bulk RNA-seqstatistical model

𝕏 PostBluesky