NeurosciencebioRxivPreprint
Near-cognate initiation generates FMRpolyG from CGG repeats in Fragile X associated Tremor Ataxia Syndrome
Yuan Zhang, M. Rebecca Glineburg, Venkatesha Basrur…·Peter K. Todd
The paper identifies and quantifies FMRpolyG, a toxic RAN translation product from FMR1 CGG repeats, using mass spectrometry in FXTAS patient samples and cell models.
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