NeuroscienceMolecular PsychiatryPeer-reviewed
Genome-wide consensus transcriptional signatures identify synaptic pruning linking Alzheimer's disease and epilepsy
Huihong Li, Zhiran Xie, Yuxuan Tian…·Xiaoyu Ji
The paper identifies a conserved microglial synaptic pruning pathway linked to Alzheimer's disease and epilepsy through genome-wide transcriptomic analysis across multiple models and human cohorts.