ZDHHC14-Mediated Palmitoylation of TBK1 Promotes Pathological Cardiac Hypertrophy via Type I Interferon Signaling Activation
Wei Zhao, Ying Yang, Gaoyuan Ge, Rui‐Xia Xu
This study identifies ZDHHC14-mediated TBK1 palmitoylation as a driver of cardiac hypertrophy through IFN-I signaling, showing therapeutic potential.
bioRxiv · Jul 26, 2026 · PreprintMolecular Biology