Generalist method to reconstruct metabolic networks from multi-omics data at large-scale
Pavan Kumar S, Subasree Sridhar, Noor Alsmadi, Radhakrishnan Mahadevan, Nirav Bhatt
The paper introduces SPECTRA, a method to reconstruct metabolic networks from multi-omics data at large-scale, improving speed and reaction inclusion across cancer cell lines, microbial reconstructions, and synthetic gut microbiota.
bioRxiv · Apr 6, 2026 · PreprintSystems Biology