Author

Hongbo Yang

Fudan UniversityORCID 0009-0004-2525-9462Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:Hi-C· 1 Organism:mouse· 1 Organism:non-human primate· 1 Approach:statistical model· 1

Frequent Co-Authors

Biyun ZhuiD· 1 shared Cheng Ye· 1 shared Chong Cui· 1 shared Dan MuiD· 1 shared Daqi Wang· 1 shared Detong ShiiD· 1 shared Feiyang XueiD· 1 shared Guangbin Sun· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetics

Biyun ZhuORCID

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2 papers

Recent·Most cited

Combination of engineered cell type-specific promoters and a high-efficiency AAV capsid restores hearing in adult DFNB1 mice model with demonstrated safety in nonhuman primate

Shao Wei Hu, Cheng Ye, Guannan Geng, Yicheng Zeng, Yihan Bao, Sen Zhang, Chong Cui, Yingting Zhang, Dan Mu, Daqi Wang, Xintai Fan, Ziting Chen, Biyun Zhu, Shuang Han, Hongxing Wang, , Yilai Shu

This paper demonstrates hearing restoration in adult DFNB1 mice using engineered promoters and an AAV capsid, with safety confirmed in nonhuman primates.

bioRxiv · Apr 18, 2026 · PreprintGenetics

Boosting the detection of enhancer-promoter loops via novel normalization methods for chromatin interaction data

Xiaotao Wang, Detong Shi, Feiyang Xue, Yunxia Liu, Hongbo Yang, Ling-Han Jiang

Raichu improves enhancer-promoter loop detection in Hi-C data by enhancing sensitivity and recovering missed loops compared to ICE normalization.

Nature Communications · Feb 3, 2026Peer-reviewedBioinformatics