Author

Jeff Vogt

Johns Hopkins UniversityORCID 0009-0004-3001-9631Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

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Jeffrey J. GrayiD· 1 shared Lee‐Shin ChuiD· 1 shared Michael ChungyouniD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperBioinformatics

Jeffrey J. GrayORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintJun 13, 2026

ProtAff: Protein Binding Affinity Prediction via LoRA-Finetuned ESM-2

Lee‐Shin Chu, Jeff Vogt, Michael Chungyoun, Jeffrey J. Gray

ProtAff predicts protein-protein binding affinity using sequence data, outperforming existing methods on an EGFR benchmark but underperforming structural methods in cross-target discrimination.

DOI 10.64898/2026.06.13.732058

humanprotein sequence

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