Molecular BiologybioRxivPreprint
Myocardial cGMP-PKG1alpha dysregulation contributes to VT pathogenesis in type II diabetes and metabolic syndrome.
Xuehong Cao, Yali Zhang, Audrey Tripp…·Jonas Galper
This study identifies cGMP reduction as a driver of VT in DMII and metabolic syndrome, showing that pharmacological modulation of cGMP-PKG1alpha pathways can reduce VT inducibility.
DOI 10.1101/2025.02.12.638003