High-throughput sequencing of unmethylated DNA (UMR-seq) reveals extensive epigenetic variation in the hypomethylome of diverse plant species
Vanessa Putland, Hannah Robinson, Judith I. M. Eglitis-Sexton, Guilherme V Yoshikawa, Jessica Hintzsche, Haylie Andrews, Stacey Andersen, Sohye Yoon, Jingyang Tong, Leroy M. Mangila, Akshya Sree, Silvia Zanini, Maximilian Schmidt, Yan Zhang, Rod J. Snowdon, , Peter A. Crisp
UMR-seq reveals epigenetic variation in plant hypomethylomes, showing UMRs are enriched in regulatory loci and improve genomic prediction and trait association mapping in wheat.
bioRxiv · Nov 4, 2026 · PreprintGenomics