BiophysicsThe Journal of General PhysiologyPeer-reviewed
Characterization of an Open-Channel Structure and Lateral Conduction Pathway in the Cation-Selective Pentameric Ligand-Gated Ion Channel, ELIC
Mark J. Arcario, Elizabeth Wu-Chen, Yuna Shim…·Wayland W.L. Cheng
The paper uses molecular dynamics simulations to analyze ion conduction in the ELIC channel, showing that a lateral fenestration is critical for cation selectivity and conductance.
DOI 10.1085/jgp.202513926