Author

Zhandos Sembay

University of Alabama at BirminghamORCID 0009-0004-6159-5076Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1

Frequent Co-Authors

Ehsan SaghapouriD· 3 shared Jake Y. CheniD· 3 shared Zongliang YueiD· 2 shared Christopher Douglas WilleyiD· 1 shared Delower HossainiD· 1 shared Fuad Al AbiriD· 1 shared Geetanjali OisheiD· 1 shared Nikhil Kurmachalam· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

Ehsan SaghapourORCID

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3 papers

Recent·Most cited

Induced ERBB response and standing FAK dependency nominate separable KRAS-combination hypotheses in pancreatic cancer

Jake Y. Chen, Ehsan Saghapour, Nikhil Kurmachalam, Geetanjali Oishe, Zhandos Sembay

This paper identifies two separable KRAS-combination partners in pancreatic cancer: an induced ERBB2/3 up-regulation and a standing FAK dependency, both computationally nominated from public data.

bioRxiv · Jul 10, 2026 · PreprintCancer Biology

MondrianMap: Navigating Gene Set Hierarchies with Multi-Resolution Enrichment Maps

Fuad Al Abir, Zongliang Yue, Ehsan Saghapour, Delower Hossain, Zhandos Sembay, Jake Y. Chen

MondrianMap provides multi-resolution visualization of gene set enrichment results, revealing directional oppositions and temporal dynamics across biological processes in cancer, aging, and exercise data.

bioRxiv · Jun 29, 2026 · PreprintSystems Biology

Explorative Discovery of Gene Signatures and Clinotypes in Glioblastoma Cancer Through GeneTerrain Knowledge Map Representation

Ehsan Saghapour, Zongliang Yue, Rahul Sharma, Sidharth Kumar, Zhandos Sembay, Christopher Douglas Willey, Jake Y. Chen

This paper introduces GTKM, a method for visualizing gene expression data in glioblastoma, showing it identifies gene patterns linked to clinical outcomes and subtypes.

bioRxiv · Apr 1, 2024 · PreprintBioinformatics