Christopher Douglas Willey

This study shows that collagen-dependent DDR1 ectodomain shedding reduces proliferative signaling in radiation-resistant glioblastoma by decreasing DDR1 phosphorylation and increasing ADAMTS1 activity.

This study identifies SON as a suppressor of circRNA biogenesis in glioblastoma, linking circRNA depletion to PKR signaling and radiation resistance.

This study identifies ST6GAL1 as a key mediator of acinar cell survival and tissue regeneration during pancreatitis by promoting cell survival pathways and tissue repair.

This study identifies 5'-tRNA halves (tiR5s) as markers of poor prognosis and therapeutic resistance in glioblastoma, linking them to disease persistence and invasive pathways.

GOALS introduces a novel framework for analyzing Gene Ontologies by discretizing them into optimal layers to enhance functional insights and visualization in biological processes.

This paper introduces GTKM, a method for visualizing gene expression data in glioblastoma, showing it identifies gene patterns linked to clinical outcomes and subtypes.

HPAanalyze is an R package that retrieves and analyzes Human Protein Atlas data, enabling exploratory analysis and visualization of protein expression data and images.